Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation

Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton and transduce signals in response to both chemical and mechanical cues. The composition, interactions, stoichiometry, and topological organization of proteins within IACs are not fully understood. To address...

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Библиографические подробности
Опубликовано в: :J Cell Biol
Главные авторы: Chastney, Megan R., Lawless, Craig, Humphries, Jonathan D., Warwood, Stacey, Jones, Matthew C., Knight, David, Jorgensen, Claus, Humphries, Martin J.
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401799/
https://ncbi.nlm.nih.gov/pubmed/32585685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202003038
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