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Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation

Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton and transduce signals in response to both chemical and mechanical cues. The composition, interactions, stoichiometry, and topological organization of proteins within IACs are not fully understood. To address...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Chastney, Megan R., Lawless, Craig, Humphries, Jonathan D., Warwood, Stacey, Jones, Matthew C., Knight, David, Jorgensen, Claus, Humphries, Martin J.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401799/
https://ncbi.nlm.nih.gov/pubmed/32585685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202003038
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