Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation

Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton and transduce signals in response to both chemical and mechanical cues. The composition, interactions, stoichiometry, and topological organization of proteins within IACs are not fully understood. To address...

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Udgivet i:J Cell Biol
Main Authors: Chastney, Megan R., Lawless, Craig, Humphries, Jonathan D., Warwood, Stacey, Jones, Matthew C., Knight, David, Jorgensen, Claus, Humphries, Martin J.
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401799/
https://ncbi.nlm.nih.gov/pubmed/32585685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202003038
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