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Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation

Integrin adhesion complexes (IACs) bridge the extracellular matrix to the actin cytoskeleton and transduce signals in response to both chemical and mechanical cues. The composition, interactions, stoichiometry, and topological organization of proteins within IACs are not fully understood. To address...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Chastney, Megan R., Lawless, Craig, Humphries, Jonathan D., Warwood, Stacey, Jones, Matthew C., Knight, David, Jorgensen, Claus, Humphries, Martin J.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401799/
https://ncbi.nlm.nih.gov/pubmed/32585685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202003038
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