Mapping axon initial segment structure and function by multiplexed proximity biotinylation

Axon initial segments (AISs) generate action potentials and regulate the polarized distribution of proteins, lipids, and organelles in neurons. While the mechanisms of AIS Na(+) and K(+) channel clustering are understood, the molecular mechanisms that stabilize the AIS and control neuronal polarity...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hamdan, Hamdan, Lim, Brian C., Torii, Tomohiro, Joshi, Abhijeet, Konning, Matthias, Smith, Cameron, Palmer, Donna J., Ng, Philip, Leterrier, Christophe, Oses-Prieto, Juan A., Burlingame, Alma L., Rasband, Matthew N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6941957/
https://ncbi.nlm.nih.gov/pubmed/31900387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13658-5
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