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Nitric oxide modulates bone anabolism through regulation of osteoblast glycolysis and differentiation

Previous studies have shown that nitric oxide (NO) supplements may prevent bone loss and fractures in preclinical models of estrogen deficiency. However, the mechanisms by which NO modulates bone anabolism remain largely unclear. Argininosuccinate lyase (ASL) is the only mammalian enzyme capable of...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Jin, Zixue, Kho, Jordan, Dawson, Brian, Jiang, Ming-Ming, Chen, Yuqing, Ali, Saima, Burrage, Lindsay C., Grover, Monica, Palmer, Donna J., Turner, Dustin L., Ng, Philip, Nagamani, Sandesh C.S., Lee, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919726/
https://ncbi.nlm.nih.gov/pubmed/33373331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138935
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