Nitric oxide modulates bone anabolism through regulation of osteoblast glycolysis and differentiation

Previous studies have shown that nitric oxide (NO) supplements may prevent bone loss and fractures in preclinical models of estrogen deficiency. However, the mechanisms by which NO modulates bone anabolism remain largely unclear. Argininosuccinate lyase (ASL) is the only mammalian enzyme capable of...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Jin, Zixue, Kho, Jordan, Dawson, Brian, Jiang, Ming-Ming, Chen, Yuqing, Ali, Saima, Burrage, Lindsay C., Grover, Monica, Palmer, Donna J., Turner, Dustin L., Ng, Philip, Nagamani, Sandesh C.S., Lee, Brendan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919726/
https://ncbi.nlm.nih.gov/pubmed/33373331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138935
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