New therapies for hemophilia

Por Pipe, Steven W.
Publicado no Hematology Am Soc Hematol Educ Program (2016)

Characterization of a genetically engineered inactivation-resistant coagulation factor VIIIa

Por Pipe, Steven W., Kaufman, Randal J.
Publicado em 1997

A Cornucopia of Therapies under Study for Hemophilia

Por Pierce, Glenn F., Pipe, Steven W.
Publicado no Mol Ther (2017)

Most Factor VIII B Domain Missense Mutations Are Unlikely to Be Causative Mutations for Severe Hemophilia A: Implications for Genotyping

Por Ogata, Kyoichi, Selvaraj, Sundar R, Miao, Hongzhi Z, Pipe, Steven W
Publicado em 2011

The role of platelets and ε-aminocaproic acid in arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome associated hemorrhage

Por Weyand, Angela C., Lombel, Rebecca M., Pipe, Steven W., Shavit, Jordan A.
Publicado no Pediatr Blood Cancer (2015)

Functional factor VIII made with von Willebrand factor at high levels in transgenic milk

Por Pipe, Steven W., Miao, Hongzhi, Butler, Stephen P., Calcaterra, Jennifer, Velander, William H.
Publicado em 2011

Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine

Por Gilbert, Gary E., Novakovic, Valerie A., Shi, Jialan, Rasmussen, Jan, Pipe, Steven W.
Publicado no Blood (2015)

Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity

Por Gilbert, Gary E., Novakovic, Valerie A., Kaufman, Randal J., Miao, Hongzhi, Pipe, Steven W.
Publicado em 2012

Life in the shadow of a dominant partner: the FVIII-VWF association and its clinical implications for hemophilia A

Por Pipe, Steven W., Montgomery, Robert R., Pratt, Kathleen P., Lenting, Peter J., Lillicrap, David
Publicado no Blood (2016)

Suppression of FVIII Inhibitor Formation in Hemophilic Mice by Delivery of Transgene Modified Apoptotic Fibroblasts

Por Su, Rui-Jun, Epp, Angela, Latchman, Yvette, Bolgiano, Doug, Pipe, Steven W, Josephson, Neil C
Publicado em 2009

Bioengineering of coagulation factor VIII for efficient expression through elimination of a dispensable disulfide loop

Por SELVARAJ, SUNDAR R, SCHELLER, ARNO N, MIAO, HONGZHI Z, KAUFMAN, RANDAL J, PIPE, STEVEN W
Publicado em 2012

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

Por Malhotra, Jyoti D., Miao, Hongzhi, Zhang, Kezhong, Wolfson, Anna, Pennathur, Subramaniam, Pipe, Steven W., Kaufman, Randal J.
Publicado em 2008

Outcomes of Mentored, Grant-Funded Fellowship Training in Hemostasis/Thrombosis: Findings from a Nested Case-Control Survey Study

Por Goldenberg, Neil A., Kruse-Jarres, Rebecca, Frick, Neil, Pipe, Steven W., Leissinger, Cindy A., Kessler, Craig M.
Publicado em 2011

A von Willebrand factor fragment containing the D′D3 domains is sufficient to stabilize coagulation factor VIII in mice

Por Yee, Andrew, Gildersleeve, Robert D., Gu, Shufang, Kretz, Colin A., McGee, Beth M., Carr, Keisha M., Pipe, Steven W., Ginsburg, David
Publicado em 2014

HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas

Por Park, Min-Jung, Iyer, Sapna, Xue, Xiang, Cunha, Juliana Bragazzi, Gu, Shufang, Moons, David, Pipe, Steven W., Williams, John A., Simeone, Diane M., Shah, Yatrik M., Omary, M. Bishr
Publicado no Gastroenterology (2018)

In vivo efficacy of platelet-delivered, high specific activity factor VIII variants

Por Greene, Teshell K., Wang, Cheng, Hirsch, Jessica D., Zhai, Li, Gewirtz, Jamie, Thornton, Michael A., Miao, Hongzhi Z., Pipe, Steven W., Kaufman, Randal J., Camire, Rodney M., Arruda, Valder R., Kowalska, M. Anna, Poncz, Mortimer
Publicado em 2010

The Enhancing Effects of the Light Chain on Heavy Chain Secretion in Split Delivery of Factor VIII Gene

Por Chen, Lingxia, Zhu, Fuxiang, Li, Juan, Lu, Hui, Jiang, Haiyan, Sarkar, Rita, Arruda, Valder R, Wang, Jinhui, Zhao, Jennifer, Pierce, Glenn F, Ding, Qiulan, Wang, Xuefeng, Wang, Hongli, Pipe, Steven W, Liu, Xiang-Qin, Xiao, Xiao, Camire, Rodney M, Xiao, Weidong
Publicado em 2007