Suppression of FVIII Inhibitor Formation in Hemophilic Mice by Delivery of Transgene Modified Apoptotic Fibroblasts

The development of inhibitory antibodies to factor VIII (FVIII) is currently the most significant complication of FVIII replacement therapy in the management of patients with severe hemophilia A. Immune tolerance protocols for the eradication of inhibitors require daily delivery of intravenous FVIII...

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Detalhes bibliográficos
Main Authors: Su, Rui-Jun, Epp, Angela, Latchman, Yvette, Bolgiano, Doug, Pipe, Steven W, Josephson, Neil C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839230/
https://ncbi.nlm.nih.gov/pubmed/19755963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.209
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