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Investigation of hFVIII Production in Mammary Glands of Transgenic Mice

Hemophilia A is an X-linked disorder affecting 1 in 10,000 males. The disease is caused by a defect or mutation of factor 8 or 9. Human factor 8 gene (hFVIII) is a relatively large gene consisting of 26 exons and approximately 2,351 amino acids with a length of 9 Kb mRNA. Expression of hFVIII in mam...

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Detalhes bibliográficos
Main Authors: Mohammadian, Tahar, Rassi, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216513/
https://ncbi.nlm.nih.gov/pubmed/25358000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2014.0008
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