Functional factor VIII made with von Willebrand factor at high levels in transgenic milk

BACKGROUND: Current manufacturing methods for recombinant human Factor VIII (rFVIII) within mammalian cell cultures are inefficient which limit the abundance needed for affordable, worldwide treatment of hemophilia A. However, rFVIII has been expressed at very high levels by the transgenic mammary g...

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Detaylı Bibliyografya
Asıl Yazarlar: Pipe, Steven W., Miao, Hongzhi, Butler, Stephen P., Calcaterra, Jennifer, Velander, William H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444248/
https://ncbi.nlm.nih.gov/pubmed/21920013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2011.04505.x
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