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Functional factor VIII made with von Willebrand factor at high levels in transgenic milk

BACKGROUND: Current manufacturing methods for recombinant human Factor VIII (rFVIII) within mammalian cell cultures are inefficient which limit the abundance needed for affordable, worldwide treatment of hemophilia A. However, rFVIII has been expressed at very high levels by the transgenic mammary g...

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Bibliografiset tiedot
Päätekijät: Pipe, Steven W., Miao, Hongzhi, Butler, Stephen P., Calcaterra, Jennifer, Velander, William H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444248/
https://ncbi.nlm.nih.gov/pubmed/21920013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2011.04505.x
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