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Life in the shadow of a dominant partner: the FVIII-VWF association and its clinical implications for hemophilia A
A normal hemostatic response to vascular injury requires both factor VIII (FVIII) and von Willebrand factor (VWF). In plasma, VWF and FVIII normally circulate as a noncovalent complex, and each has a critical function in the maintenance of hemostasis. Furthermore, the interaction between VWF and FVI...
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| Publicado no: | Blood |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073181/ https://ncbi.nlm.nih.gov/pubmed/27587878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-04-713289 |
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