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Utility of a high VWF:FVIII ratio in preventing FVIII accumulation: a study in VWF-deficient mice

Treatment of von Willebrand disease typically requires multiple infusions of von Willebrand factor (VWF)/factor VIII (FVIII) concentrate. Accumulation of FVIII is a clinical concern due to potential risk for thromboembolism. This study sought to determine whether VWF/FVIII concentrate of high VWF:FV...

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Detalhes bibliográficos
Publicado no:Blood Coagul Fibrinolysis
Main Authors: Raquet, Elmar, Stockschlaeder, Marcus, Mueller-Cohrs, Jochen, Zollner, Sabine, Pragst, Ingo, Dickneite, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams And Wilkins 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500654/
https://ncbi.nlm.nih.gov/pubmed/25767894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000269
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