C1-esterase inhibitor treatment: preclinical safety aspects on the potential prothrombotic risk

Human plasma-derived C1-esterase inhibitor (C1–INH) is an efficacious and safe treatment for hereditary angioedema. However, thrombotic events in subjects treated with C1–INH at recommended or offlabel, high doses have been reported. In this study, we addressed the potential prothrombotic risk of C1...

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Dettagli Bibliografici
Pubblicato in:Thromb Haemost
Autori principali: Schürmann, Daniel, Herzog, Eva, Raquet, Elmar, Nolte, Marc W., May, Frauke, Müller-Cohrs, Jochen, Björkqvist, Jenny, Dickneite, Gerhard, Pragst, Ingo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Schattauer GmbH 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374987/
https://ncbi.nlm.nih.gov/pubmed/25103795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/th13-06-0469
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