VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease

During posttranslational modifications of von Willebrand factor (VWF), the VWF propeptide (VWFpp) is cleaved. The ratio between VWFpp and VWF antigen (VWF:Ag) and the ratio between factor VIII (FVIII:C) and VWF:Ag may be used to assess synthesis and clearance of VWF. We analyzed the contribution of...

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Detalhes bibliográficos
Main Authors: Eikenboom, Jeroen, Federici, Augusto B., Dirven, Richard J., Castaman, Giancarlo, Rodeghiero, Francesco, Budde, Ulrich, Schneppenheim, Reinhard, Batlle, Javier, Canciani, Maria Teresa, Goudemand, Jenny, Peake, Ian, Goodeve, Anne, Tosetto, Alberto, Meyer, Dominique, Fressinaud, Edith, Mazurier, Claudine, Ingerslev, Jørgen, Vorlova, Zdena, Habart, David, Holmberg, Lars, Lethagen, Stefan, Pasi, John, Hill, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191434/
https://ncbi.nlm.nih.gov/pubmed/23349392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-09-455089
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