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Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine

Thrombin-stimulated platelets expose very little phosphatidylserine (PS) but express binding sites for factor VIII (fVIII), casting doubt on the role of exposed PS as the determinant of binding sites. We previously reported that fVIII binding sites are increased three- to sixfold when soluble fibrin...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Gilbert, Gary E., Novakovic, Valerie A., Shi, Jialan, Rasmussen, Jan, Pipe, Steven W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559935/
https://ncbi.nlm.nih.gov/pubmed/26162408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-620245
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