Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine

Thrombin-stimulated platelets expose very little phosphatidylserine (PS) but express binding sites for factor VIII (fVIII), casting doubt on the role of exposed PS as the determinant of binding sites. We previously reported that fVIII binding sites are increased three- to sixfold when soluble fibrin...

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Veröffentlicht in:Blood
Hauptverfasser: Gilbert, Gary E., Novakovic, Valerie A., Shi, Jialan, Rasmussen, Jan, Pipe, Steven W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Thrombosis and Hemostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559935/
https://ncbi.nlm.nih.gov/pubmed/26162408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-620245
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