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The factor VIII C1 domain contributes to platelet binding
Activated factor VIII (FVIIIa) forms a procoagulant complex with factor IXa on negatively charged membranes, including activated platelet surfaces. Membrane attachment involves the FVIII C2 domain; involvement of the adjacent C1 domain has not been established. Binding of recombinant FVIII C1C2 and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200805/ https://ncbi.nlm.nih.gov/pubmed/17916745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-068957 |
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