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Fibrin activates GPVI in human and mouse platelets
The glycoprotein VI (GPVI)-Fc receptor γ (FcRγ) chain is the major platelet signaling receptor for collagen. Paradoxically, in a FeCl(3) injury model, occlusion, but not initiation of thrombus formation, is delayed in GPVI-deficient and GPVI-depleted mice. In this study, we demonstrate that GPVI is...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582337/ https://ncbi.nlm.nih.gov/pubmed/26282541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-04-641654 |
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