Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

Soluble glycoprotein VI (sGPVI) is shed from the platelet surface and is a marker of platelet activation in thrombotic conditions. We assessed sGPVI levels together with patient and clinical parameters in acute and chronic inflammatory conditions, including patients with thermal injury and inflammat...

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Bibliografski detalji
Izdano u:Blood Adv
Glavni autori: Montague, Samantha J., Delierneux, Céline, Lecut, Christelle, Layios, Nathalie, Dinsdale, Robert J., Lee, Christine S.-M., Poulter, Natalie S., Andrews, Robert K., Hampson, Peter, Wearn, Christopher M., Maes, Nathalie, Bishop, Jonathan, Bamford, Amy, Gardiner, Chris, Lee, Woei Ming, Iqbal, Tariq, Moiemen, Naiem, Watson, Steve P., Oury, Cécile, Harrison, Paul, Gardiner, Elizabeth E.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2018
Teme:
Thrombosis and Hemostasis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812322/
https://ncbi.nlm.nih.gov/pubmed/29437639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011171
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