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Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

Soluble glycoprotein VI (sGPVI) is shed from the platelet surface and is a marker of platelet activation in thrombotic conditions. We assessed sGPVI levels together with patient and clinical parameters in acute and chronic inflammatory conditions, including patients with thermal injury and inflammat...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Montague, Samantha J., Delierneux, Céline, Lecut, Christelle, Layios, Nathalie, Dinsdale, Robert J., Lee, Christine S.-M., Poulter, Natalie S., Andrews, Robert K., Hampson, Peter, Wearn, Christopher M., Maes, Nathalie, Bishop, Jonathan, Bamford, Amy, Gardiner, Chris, Lee, Woei Ming, Iqbal, Tariq, Moiemen, Naiem, Watson, Steve P., Oury, Cécile, Harrison, Paul, Gardiner, Elizabeth E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812322/
https://ncbi.nlm.nih.gov/pubmed/29437639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011171
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