Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI

Soluble glycoprotein VI (sGPVI) is shed from the platelet surface and is a marker of platelet activation in thrombotic conditions. We assessed sGPVI levels together with patient and clinical parameters in acute and chronic inflammatory conditions, including patients with thermal injury and inflammat...

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Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Montague, Samantha J., Delierneux, Céline, Lecut, Christelle, Layios, Nathalie, Dinsdale, Robert J., Lee, Christine S.-M., Poulter, Natalie S., Andrews, Robert K., Hampson, Peter, Wearn, Christopher M., Maes, Nathalie, Bishop, Jonathan, Bamford, Amy, Gardiner, Chris, Lee, Woei Ming, Iqbal, Tariq, Moiemen, Naiem, Watson, Steve P., Oury, Cécile, Harrison, Paul, Gardiner, Elizabeth E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2018
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812322/
https://ncbi.nlm.nih.gov/pubmed/29437639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011171
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