Fibrin and D-dimer bind to monomeric GPVI

Fibrin has recently been shown to activate platelets through the immunoglobulin receptor glycoprotein VI (GPVI). In the present study, we show that spreading of human platelets on fibrin is abolished in patients deficient in GPVI, confirming that fibrin activates human platelets through the immunogl...

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Detaylı Bibliyografya
Yayımlandı:Blood Adv
Asıl Yazarlar: Onselaer, Marie-Blanche, Hardy, Alexander T., Wilson, Clare, Sanchez, Ximena, Babar, Amir K., Miller, Jeanette L. C., Watson, Callum N., Watson, Stephanie K., Bonna, Arkadiusz, Philippou, Helen, Herr, Andrew B., Mezzano, Diego, Ariëns, Robert A. S., Watson, Steve P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2017
Konular:
Platelets and Thrombopoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728468/
https://ncbi.nlm.nih.gov/pubmed/29296791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017007732
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