MicroRNA-130b attenuates dexamethasone-induced increase of lipid accumulation in porcine preadipocytes by suppressing PPAR-γ expression

Por Pan, Shifeng, Cui, Yixin, Dong, Xuan, Zhang, Tangjie, Xing, Hua
Publicado no Oncotarget (2017)

Expression of hepatic miRNAs targeting porcine glucocorticoid receptor (GR) 3′UTR in the neonatal piglets under a maternal gestational betaine supplementation

Por Cai, Demin, Liu, Haoyu, Yuan, Mengjie, Pan, Shifeng, Jia, Yimin, Zhao, Ruqian
Publicado no Data Brief (2015)

Maternal betaine supplementation during gestation modifies hippocampal expression of GR and its regulatory miRNAs in neonatal piglets

Por SUN, Qinwei, LI, Xi, JIA, Yimin, PAN, Shifeng, LI, Runsheng, YANG, Xiaojing, ZHAO, Ruqian
Publicado no J Vet Med Sci (2016)

Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modifi...

Por Cai, Demin, Yuan, Mengjie, Liu, Haoyu, Pan, Shifeng, Ma, Wenqiang, Hong, Jian, Zhao, Ruqian
Publicado no Nutrients (2016)

Intravenous injection of microvesicle-delivery miR-130b alleviates high-fat diet-induced obesity in C57BL/6 mice through translational repression of PPAR-γ

Por Pan, Shifeng, Yang, Xiaojing, Jia, Yimin, Li, Yue, Chen, Rirong, Wang, Min, Cai, Demin, Zhao, Ruqian
Publicado no J Biomed Sci (2015)

Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice

Por Hong, Jian, Jia, Yimin, Pan, Shifeng, Jia, Longfei, Li, Huifang, Han, Zhenqiang, Cai, Demin, Zhao, Ruqian
Publicado no Oncotarget (2016)

Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors

Por Cheng, Dai, Liu, Jun, Han, Dong, Zhang, Guobao, Gao, Wenqi, Hsieh, Mindy H., Ng, Nicholas, Kasibhatla, Shailaja, Tompkins, Celin, Li, Jie, Steffy, Auzon, Sun, Fangxian, Li, Chun, Seidel, H. Martin, Harris, Jennifer L., Pan, Shifeng
Publicado no ACS Med Chem Lett (2016)

Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator

Por Pan, Shifeng, Gray, Nathanael S., Gao, Wenqi, Mi, Yuan, Fan, Yi, Wang, Xing, Tuntland, Tove, Che, Jianwei, Lefebvre, Sophie, Chen, Yu, Chu, Alan, Hinterding, Klaus, Gardin, Anne, End, Peter, Heining, Peter, Bruns, Christian, Cooke, Nigel G., Nuesslein-Hildesheim, Barbara
Publicado em 2013

Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

Por Jiang, Xiaomo, Hao, Huai-Xiang, Growney, Joseph D., Woolfenden, Steve, Bottiglio, Cindy, Ng, Nicholas, Lu, Bo, Hsieh, Mindy H., Bagdasarian, Linda, Meyer, Ronald, Smith, Timothy R., Avello, Monika, Charlat, Olga, Xie, Yang, Porter, Jeffery A., Pan, Shifeng, Liu, Jun, McLaughlin, Margaret E., Cong, Feng
Publicado em 2013

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

Por Miller, Andrew T., Dahlberg, Carol, Sandberg, Mark L., Wen, Ben G., Beisner, Daniel R., Hoerter, John A. H., Parker, Albert, Schmedt, Christian, Stinson, Monique, Avis, Jacqueline, Cienfuegos, Cynthia, McPate, Mark, Tranter, Pamela, Gosling, Martin, Groot-Kormelink, Paul J., Dawson, Janet, Pan, Shifeng, Tian, Shin-Shay, Seidel, H. Martin, Cooke, Michael P.
Publicado no PLoS One (2015)

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Por Pan, Shifeng, Wu, Xu, Jiang, Jiqing, Gao, Wenqi, Wan, Yongqin, Cheng, Dai, Han, Dong, Liu, Jun, Englund, Nathan P., Wang, Yan, Peukert, Stefan, Miller-Moslin, Karen, Yuan, Jing, Guo, Ribo, Matsumoto, Melissa, Vattay, Anthony, Jiang, Yun, Tsao, Jeffrey, Sun, Fangxian, Pferdekamper, AnneMarie C., Dodd, Stephanie, Tuntland, Tove, Maniara, Wieslawa, Kelleher, Joseph F., Yao, Yung-mae, Warmuth, Markus, Williams, Juliet, Dorsch, Marion
Publicado em 2010

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Por Buonamici, Silvia, Williams, Juliet, Morrissey, Michael, Wang, Anlai, Guo, Ribo, Vattay, Anthony, Hsiao, Kathy, Yuan, Jing, Green, John, Ospina, Beatrice, Yu, Qunyan, Ostrom, Lance, Fordjour, Paul, Anderson, Dustin L., Monahan, John E., Kelleher, Joseph F., Peukert, Stefan, Pan, Shifeng, Wu, Xu, Maira, Sauveur-Michel, Garcia-Echeverria, Carlos, Briggs, Kimberly J., Watkins, D. Neil, Yao, Yung-mae, Lengauer, Christoph, Warmuth, Markus, Sellers, William R., Dorsch, Marion
Publicado em 2010

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Por Liu, Jun, Pan, Shifeng, Hsieh, Mindy H., Ng, Nicholas, Sun, Fangxian, Wang, Tao, Kasibhatla, Shailaja, Schuller, Alwin G., Li, Allen G., Cheng, Dai, Li, Jie, Tompkins, Celin, Pferdekamper, AnneMarie, Steffy, Auzon, Cheng, Jane, Kowal, Colleen, Phung, Van, Guo, Guirong, Wang, Yan, Graham, Martin P., Flynn, Shannon, Brenner, J. Chad, Li, Chun, Villarroel, M. Cristina, Schultz, Peter G., Wu, Xu, McNamara, Peter, Sellers, William R., Petruzzelli, Lilli, Boral, Anthony L., Seidel, H. Martin, McLaughlin, Margaret E., Che, Jianwei, Carey, Thomas E., Vanasse, Gary, Harris, Jennifer L.
Publicado em 2013