Biophysical Investigation of the Mode of Inhibition of Tetramic Acids, the Allosteric Inhibitors of Undecaprenyl Pyrophosphate Synthase

par Lee, Lac V., Granda, Brian, Dean, Karl, Tao, Jianshi, Liu, Eugene, Zhang, Rui, Peukert, Stefan, Wattanasin, Sompong, Xie, Xiaoling, Ryder, Neil S., Tommasi, Ruben, Deng, Gejing
Publié 2010

Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists

par Peukert, Stefan, Hughes, Richard, Nunez, Jill, He, Guo, Yan, Zhao, Jain, Rishi, Llamas, Luis, Luchansky, Sarah, Carlson, Adam, Liang, Guiqing, Kunjathoor, Vidya, Pietropaolo, Mike, Shapiro, Jeffrey, Castellana, Anja, Wu, Xiaoping, Bose, Avirup
Publié 2014

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

par Pan, Shifeng, Wu, Xu, Jiang, Jiqing, Gao, Wenqi, Wan, Yongqin, Cheng, Dai, Han, Dong, Liu, Jun, Englund, Nathan P., Wang, Yan, Peukert, Stefan, Miller-Moslin, Karen, Yuan, Jing, Guo, Ribo, Matsumoto, Melissa, Vattay, Anthony, Jiang, Yun, Tsao, Jeffrey, Sun, Fangxian, Pferdekamper, AnneMarie C., Dodd, Stephanie, Tuntland, Tove, Maniara, Wieslawa, Kelleher, Joseph F., Yao, Yung-mae, Warmuth, Markus, Williams, Juliet, Dorsch, Marion
Publié 2010

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

par Buonamici, Silvia, Williams, Juliet, Morrissey, Michael, Wang, Anlai, Guo, Ribo, Vattay, Anthony, Hsiao, Kathy, Yuan, Jing, Green, John, Ospina, Beatrice, Yu, Qunyan, Ostrom, Lance, Fordjour, Paul, Anderson, Dustin L., Monahan, John E., Kelleher, Joseph F., Peukert, Stefan, Pan, Shifeng, Wu, Xu, Maira, Sauveur-Michel, Garcia-Echeverria, Carlos, Briggs, Kimberly J., Watkins, D. Neil, Yao, Yung-mae, Lengauer, Christoph, Warmuth, Markus, Sellers, William R., Dorsch, Marion
Publié 2010