INTERSECTINg Pathways in Cell Biology

gan O'Bryan, John P.
Cyhoeddwyd 2010

Pharmacological Targeting of RAS: Recent Success with Direct Inhibitors.

gan O’Bryan, John P.
Cyhoeddwyd yn Pharmacol Res (2018)

Intersectin 1 is required for neuroblastoma tumorigenesis

gan Russo, Angela, O'Bryan, John P.
Cyhoeddwyd 2012

Probing RAS function with Monobodies

gan Khan, Imran, O’Bryan, John P.
Cyhoeddwyd yn Methods Mol Biol (2021)

Bimolecular Fluorescence Complementation

gan Wong, Katy A., O'Bryan, John P.
Cyhoeddwyd 2011

Intersectin scaffold proteins and their role in cell signaling and endocytosis

gan Herrero-Garcia, Erika, O’Bryan., John P.
Cyhoeddwyd yn Biochim Biophys Acta (2016)

Direct Inhibition of RAS: Quest for the Holy Grail?

gan Spencer-Smith, Russell, O’Bryan, John P.
Cyhoeddwyd yn Semin Cancer Biol (2017)

Inhibition of RAS: proven and potential vulnerabilities

gan Zuberi, Mariyam, Khan, Imran, O’Bryan, John P.
Cyhoeddwyd yn Biochem Soc Trans (2020)

Emerging Roles for Intersectin (ITSN) in Regulating Signaling and Disease Pathways

gan Hunter, Michael P., Russo, Angela, O’Bryan, John P.
Cyhoeddwyd 2013

Receptor Tyrosine Kinase Ubiquitylation Involves the Dynamic Regulation of Cbl-Spry2 by Intersectin 1 and the Shp2 Tyrosine Phosphatase

gan Okur, Mustafa Nazir, Russo, Angela, O'Bryan, John P.
Cyhoeddwyd 2014

Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo

gan Khan, Imran, Spencer-Smith, Russell, O’Bryan, John P.
Cyhoeddwyd yn Oncogene (2018)

Therapeutic Targeting of RAS: New Hope for Drugging the “Undruggable”

gan Khan, Imran, Rhett, J. Matthew, O’Bryan, John P.
Cyhoeddwyd yn Biochim Biophys Acta Mol Cell Res (2019)

Biology, Pathology, and Therapeutic Targeting of RAS

gan Rhett, J. Matthew, Khan, Imran, O’Bryan, John P.
Cyhoeddwyd yn Adv Cancer Res (2020)

Phosphatidylinositol 3-kinase, Class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis

gan Russo, Angela, Okur, Mustafa Nazir, Bosland, Maarten, O'Bryan, John P.
Cyhoeddwyd yn Cancer Lett (2015)

Targeting the α4-α5 interface of RAS results in multiple levels of inhibition

gan Spencer-Smith, Russell, Li, Lie, Prasad, Sheela, Koide, Akiko, Koide, Shohei, O'Bryan, John P.
Cyhoeddwyd yn Small GTPases (2017)

Cooperative Role of Caveolin-1 and C-Terminal Src Kinase Binding Protein in C-Terminal Src Kinase-Mediated Negative Regulation of c-Src

gan Place, Aaron T., Chen, Zhenlong, Bakhshi, Farnaz R., Liu, Guoquan, O'Bryan, John P., Minshall, Richard D.
Cyhoeddwyd 2011

Cardiac-Specific Expression of the Tetracycline Transactivator Confers Increased Heart Function and Survival Following Ischemia Reperfusion Injury

gan Elsherif, Laila, Wang, Xuerong, Grachoff, Milana, Wolska, Beata M., Geenen, David L., O'Bryan, John P.
Cyhoeddwyd 2012

A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation

gan Wong, Katy A., Russo, Angela, Wang, Xuerong, Chen, Yun-Ju, Lavie, Arnon, O'Bryan, John P.
Cyhoeddwyd 2012

Silencing Intersectin 1 Slows Orthotopic Neuroblastoma Growth in Mice

gan Harris, Jamie, Herrero-Garcia, Erika, Russo, Angela, Kajdacsy-Balla, Andre, O’Bryan, John P., Chiu, Bill
Cyhoeddwyd yn J Pediatr Hematol Oncol (2017)

Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity

gan Burmeister, Brian T., Wang, Li, Gold, Matthew G., Skidgel, Randal A., O'Bryan, John P., Carnegie, Graeme K.
Cyhoeddwyd yn J Biol Chem (2015)