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Inhibition of RAS: proven and potential vulnerabilities
RAS is a membrane localized small GTPase frequently mutated in human cancer. As such, RAS has been a focal target for developing cancer therapeutics since its discovery nearly four decades ago. However, efforts to directly target RAS have been challenging due to the apparent lack of readily discerna...
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| Publié dans: | Biochem Soc Trans |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7875515/ https://ncbi.nlm.nih.gov/pubmed/32869838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190023 |
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