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Biology, Pathology, and Therapeutic Targeting of RAS

RAS was identified as a human oncogene in the early 1980’s and found to be mutated in nearly 30% of all human cancers. More importantly, however, RAS plays a central role in driving tumor development and maintenance. Despite decades of effort, there remain no FDA approved drugs that directly inhibit...

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Enregistré dans:
Détails bibliographiques
Publié dans:Adv Cancer Res
Auteurs principaux: Rhett, J. Matthew, Khan, Imran, O’Bryan, John P.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393484/
https://ncbi.nlm.nih.gov/pubmed/32723567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2020.05.002
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