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Biology, Pathology, and Therapeutic Targeting of RAS
RAS was identified as a human oncogene in the early 1980’s and found to be mutated in nearly 30% of all human cancers. More importantly, however, RAS plays a central role in driving tumor development and maintenance. Despite decades of effort, there remain no FDA approved drugs that directly inhibit...
Gardado en:
| Publicado en: | Adv Cancer Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7393484/ https://ncbi.nlm.nih.gov/pubmed/32723567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2020.05.002 |
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