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Probing RAS function with Monobodies

ii. RAS is frequently mutated in human cancers with nearly 27% of all cancers harboring mutations in one of three RAS isoforms (KRAS, HRAS or NRAS). Furthermore, RAS proteins are critical oncogenic drivers of tumorigenesis. As such, RAS has been a prime focus for development of targeted cancer thera...

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Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Khan, Imran, O’Bryan, John P.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121162/
https://ncbi.nlm.nih.gov/pubmed/33977484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-1190-6_17
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