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Pharmacological Targeting of RAS: Recent Success with Direct Inhibitors.
RAS has long been viewed as undruggable due to its lack of deep pockets for binding of small molecule inhibitors. However, recent successes in the development of direct RAS inhibitors suggest that the goal of pharmacological inhibition of RAS in patients may soon be realized. This review will discus...
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| Опубликовано в: : | Pharmacol Res |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360110/ https://ncbi.nlm.nih.gov/pubmed/30366101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.10.021 |
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