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Pharmacological Targeting of RAS: Recent Success with Direct Inhibitors.
RAS has long been viewed as undruggable due to its lack of deep pockets for binding of small molecule inhibitors. However, recent successes in the development of direct RAS inhibitors suggest that the goal of pharmacological inhibition of RAS in patients may soon be realized. This review will discus...
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| Publicado no: | Pharmacol Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6360110/ https://ncbi.nlm.nih.gov/pubmed/30366101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2018.10.021 |
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