Silencing Intersectin 1 Slows Orthotopic Neuroblastoma Growth in Mice

Neuroblastoma accounts for 15% of all pediatric cancer deaths. Intersectin 1(ITSN1), a scaffold protein involved in phosphoinositide 3-kinase(PI3K) signaling, regulates neuroblastoma cells independent of MYCN status. We hypothesize that by silencing ITSN1 in neuroblastoma cells, tumor growth will be...

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Bibliografiske detaljer
Udgivet i:J Pediatr Hematol Oncol
Main Authors: Harris, Jamie, Herrero-Garcia, Erika, Russo, Angela, Kajdacsy-Balla, Andre, O’Bryan, John P., Chiu, Bill
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656511/
https://ncbi.nlm.nih.gov/pubmed/28787396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000931
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