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Silencing Intersectin 1 Slows Orthotopic Neuroblastoma Growth in Mice
Neuroblastoma accounts for 15% of all pediatric cancer deaths. Intersectin 1(ITSN1), a scaffold protein involved in phosphoinositide 3-kinase(PI3K) signaling, regulates neuroblastoma cells independent of MYCN status. We hypothesize that by silencing ITSN1 in neuroblastoma cells, tumor growth will be...
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| Publicado en: | J Pediatr Hematol Oncol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5656511/ https://ncbi.nlm.nih.gov/pubmed/28787396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000931 |
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