Elevated kynurenine pathway metabolism during neurodevelopment: Implications for brain and behavior

Por Notarangelo, Francesca M., Pocivavsek, Ana
Publicado no Neuropharmacology (2016)

Restraint stress during pregnancy rapidly raises kynurenic acid levels in mouse placenta and fetal brain

Por Notarangelo, Francesca M., Schwarcz, Robert
Publicado no Dev Neurosci (2017)

KYNURENIC ACID AND 3-HYDROXYKYNURENINE PRODUCTION FROM D-KYNURENINE IN MICE

Por Wang, Xiao-Dan, Notarangelo, Francesca M., Wang, Ji-Zuo, Schwarcz, Robert
Publicado em 2012

Role of D-amino acid oxidase in the production of kynurenine pathway metabolites from D-tryptophan in mice

Por Notarangelo, Francesca M., Wang, Xiao-Dan, Horning, Kyle J., Schwarcz, Robert
Publicado no J Neurochem (2016)

GC/MS/MS DETECTION OF EXTRACELLULAR KYNURENINE AND RELATED METABOLITES IN NORMAL AND LESIONED RAT BRAIN

Por Notarangelo, Francesca M., Wu, Hui-Qiu, Macherone, Anthony, Graham, David R., Schwarcz, Robert
Publicado em 2011

Tryptophan 2,3-Dioxygenfase and Indoleamine 2,3-Dioxygenase 1 Make Separate, Tissue-Specific Contributions to Basal and Inflammation-Induced Kynurenine Pathway Metabolism in Mice

Por Larkin, Paul B., Sathyasaikumar, Korrapati V., Notarangelo, Francesca M., Funakoshi, Hiroshi, Nakamura, Toshikazu, Schwarcz, Robert, Muchowski, Paul J.
Publicado no Biochim Biophys Acta (2016)

Influence of plasma cytokines on kynurenine and kynurenic acid in schizophrenia

Por Chiappelli, Joshua, Notarangelo, Francesca M., Pocivavsek, Ana, Thomas, Marian A. R., Rowland, Laura M., Schwarcz, Robert, Hong, L. Elliot
Publicado no Neuropsychopharmacology (2018)

Stress-Induced Increase in Kynurenic Acid as a Potential Biomarker for Patients With Schizophrenia and Distress Intolerance

Por Chiappelli, Joshua, Pocivavsek, Ana, Nugent, Katie L., Notarangelo, Francesca M., Kochunov, Peter, Rowland, Laura M., Schwarcz, Robert, Hong, L. Elliot
Publicado no JAMA Psychiatry (2014)

Enzymatic transamination of d-kynurenine generates kynurenic acid in rat and human brain

Por Pérez-de la Cruz, Veronica, Amori, Laura, Sathyasaikumar, Korrapati V., Wang, Xiao-Dan, Notarangelo, Francesca M., Wu, Hui-Qiu, Schwarcz, Robert
Publicado em 2012

Targeted Deletion of Kynurenine 3-Monooxygenase in Mice: A NEW TOOL FOR STUDYING KYNURENINE PATHWAY METABOLISM IN PERIPHERY AND BRAIN

Por Giorgini, Flaviano, Huang, Shao-Yi, Sathyasaikumar, Korrapati V., Notarangelo, Francesca M., Thomas, Marian A. R., Tararina, Margarita, Wu, Hui-Qiu, Schwarcz, Robert, Muchowski, Paul J.
Publicado em 2013

Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia

Por Chiappelli, Joshua, Rowland, Laura M., Notarangelo, Francesca M., Wijtenburg, S. Andrea, Thomas, Marian A. R., Pocivavsek, Ana, Jones, Aaron, Wisner, Krista, Kochunov, Peter, Schwarcz, Robert, Hong, L. Elliot
Publicado no Neuropsychopharmacology (2018)

Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites

Por Breda, Carlo, Sathyasaikumar, Korrapati V., Sograte Idrissi, Shama, Notarangelo, Francesca M., Estranero, Jasper G., Moore, Gareth G. L., Green, Edward W., Kyriacou, Charalambos P., Schwarcz, Robert, Giorgini, Flaviano
Publicado no Proc Natl Acad Sci U S A (2016)

Quinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART

Por Drewes, Julia L., Meulendyke, Kelly A., Liao, Zhaohao, Witwer, Kenneth W., Gama, Lucio, Ubaida-Mohien, Ceereena, Li, Ming, Notarangelo, Francesca M., Tarwater, Patrick M., Schwarcz, Robert, Graham, David R., Zink, M. Christine
Publicado no J Neurovirol (2015)

Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals

Por Clark, Sarah M., Pocivavsek, Ana, Nicholson, James D., Notarangelo, Francesca M., Langenberg, Patricia, McMahon, Robert P., Kleinman, Joel E., Hyde, Thomas M., Stiller, John, Postolache, Teodor T., Schwarcz, Robert, Tonelli, Leonardo H.
Publicado no J Psychiatry Neurosci (2016)

Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration

Por Zwilling, Daniel, Huang, Shao-Yi, Sathyasaikumar, Korrapati V., Notarangelo, Francesca M., Guidetti, Paolo, Wu, Hui-Qiu, Lee, Jason, Truong, Jennifer, Andrews-Zwilling, Yaisa, Hsieh, Eric W., Louie, Jamie Y., Wu, Tiffany, Scearce-Levie, Kimberly, Patrick, Christina, Adame, Anthony, Giorgini, Flaviano, Moussaoui, Saliha, Laue, Grit, Rassoulpour, Arash, Flik, Gunnar, Huang, Yadong, Muchowski, Joseph M., Masliah, Eliezer, Schwarcz, Robert, Muchowski, Paul J.
Publicado em 2011