Tryptophan 2,3-Dioxygenfase and Indoleamine 2,3-Dioxygenase 1 Make Separate, Tissue-Specific Contributions to Basal and Inflammation-Induced Kynurenine Pathway Metabolism in Mice

In mammals, the majority of the essential amino acid tryptophan is degraded via the kynurenine pathway (KP). Several KP metabolites play distinct physiological roles, often linked to immune system functions, and may also be causally involved in human diseases including neurodegenerative disorders, s...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Biochim Biophys Acta
Κύριοι συγγραφείς: Larkin, Paul B., Sathyasaikumar, Korrapati V., Notarangelo, Francesca M., Funakoshi, Hiroshi, Nakamura, Toshikazu, Schwarcz, Robert, Muchowski, Paul J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2016
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808460/
https://ncbi.nlm.nih.gov/pubmed/27392942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.07.002
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