Targeted Deletion of Kynurenine 3-Monooxygenase in Mice: A NEW TOOL FOR STUDYING KYNURENINE PATHWAY METABOLISM IN PERIPHERY AND BRAIN

Kynurenine 3-monooxygenase (KMO), a pivotal enzyme in the kynurenine pathway (KP) of tryptophan degradation, has been suggested to play a major role in physiological and pathological events involving bioactive KP metabolites. To explore this role in greater detail, we generated mice with a targeted...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Giorgini, Flaviano, Huang, Shao-Yi, Sathyasaikumar, Korrapati V., Notarangelo, Francesca M., Thomas, Marian A. R., Tararina, Margarita, Wu, Hui-Qiu, Schwarcz, Robert, Muchowski, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868768/
https://ncbi.nlm.nih.gov/pubmed/24189070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.503813
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados