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Role of D-amino acid oxidase in the production of kynurenine pathway metabolites from D-tryptophan in mice

The kynurenine pathway (KP), the major catabolic route of the essential amino acid L-tryptophan (L-TRP), contains several neuroactive compounds, including kynurenic acid (KYNA), 3-hydroxykynurenine (3-HK) and quinolinic acid (QUIN). The role of the D-enantiomer (D-TRP) in KP metabolism has received...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Notarangelo, Francesca M., Wang, Xiao-Dan, Horning, Kyle J., Schwarcz, Robert
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902784/
https://ncbi.nlm.nih.gov/pubmed/26661897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13455
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