A Specific Mechanism for Non-Specific Activation in Reporter-Gene Assays

מאת Auld, Douglas S., Thorne, Natasha, Nguyen, Dac-Trung, Inglese, James
יצא לאור 2008

Dealing with the Data Deluge: Handling the Multitude Of Chemical Biology Data Sources

מאת Guha, Rajarshi, Nguyen, Dac-Trung, Southall, Noel, Jadhav, Ajit
הוצא לאור ב Curr Protoc Chem Biol (2012)

A Grid Algorithm for High Throughput Fitting of Dose-Response Curve Data

מאת Wang, Yuhong, Jadhav, Ajit, Southal, Noel, Huang, Ruili, Nguyen, Dac-Trung
יצא לאור 2010

Phenotypically Similar Rare Disease Identification from an Integrative Knowledge Graph for Data Harmonization: Preliminary Study

מאת Zhu, Qian, Nguyen, Dac-Trung, Alyea, Gioconda, Hanson, Karen, Sid, Eric, Pariser, Anne
הוצא לאור ב JMIR Med Inform (2020)

An integrative knowledge graph for rare diseases, derived from the Genetic and Rare Diseases Information Center (GARD)

מאת Zhu, Qian, Nguyen, Dac-Trung, Grishagin, Ivan, Southall, Noel, Sid, Eric, Pariser, Anne
הוצא לאור ב J Biomed Semantics (2020)

Predicting liver cytosol stability of small molecules

מאת Shah, Pranav, Siramshetty, Vishal B., Zakharov, Alexey V., Southall, Noel T., Xu, Xin, Nguyen, Dac-Trung
הוצא לאור ב J Cheminform (2020)

A High Throughput Screening Assay for Assessing Viability of Cryptococcus neoformans under Nutrient Starvation Condition

מאת Dehdashti, Seameen J., Abbott, Jennifer, Nguyen, Dac-Trung, McKew, John C., Williamson, Peter R., Zheng, Wei
הוצא לאור ב Anal Bioanal Chem (2013)

The NCGC Pharmaceutical Collection: A comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics

מאת Huang, Ruili, Southall, Noel, Wang, Yuhong, Yasgar, Adam, Shinn, Paul, Jadhav, Ajit, Nguyen, Dac-Trung, Austin, Christopher P.
יצא לאור 2011

A Quantitative High Throughput Assay for Identifying Gametocytocidal Compounds

מאת Tanaka, Takeshi Q., Dehdashti, Seameen J., Nguyen, Dac-Trung, McKew, John C., Zheng, Wei, Williamson, Kim C.
יצא לאור 2013

Weighted Feature Significance: A Simple, Interpretable Model of Compound Toxicity Based on the Statistical Enrichment of Structural Features

מאת Huang, Ruili, Southall, Noel, Xia, Menghang, Cho, Ming-Hsuang, Jadhav, Ajit, Nguyen, Dac-Trung, Inglese, James, Tice, Raymond R., Austin, Christopher P.
יצא לאור 2009

DrugCentral 2018: an update

מאת Ursu, Oleg, Holmes, Jayme, Bologa, Cristian G, Yang, Jeremy J, Mathias, Stephen L, Stathias, Vasileios, Nguyen, Dac-Trung, Schürer, Stephan, Oprea, Tudor
הוצא לאור ב Nucleic Acids Res (2019)

Potent and Selective Small Molecule Inhibitors of Specific Isoforms of Cdc2-like Kinases (Clk) and Dual Specificity Tyrosine-Phosphorylation-Regulated Kinases (Dyrk)

מאת Rosenthal, Andrew S., Tanega, Cordelle, Shen, Min, Mott, Bryan T., Bougie, James M., Nguyen, Dac-Trung, Misteli, Tom, Auld, Douglas S., Maloney, David J., Thomas, Craig J.
יצא לאור 2011

Advancing precision medicine with personalized drug screening

מאת Gorshkov, Kirill, Chen, Catherine Z., Marshall, Raisa E., Mihatov, Nino, Choi, Yong, Nguyen, Dac-Trung, Southall, Noel, Chen, Kevin, Park, John K., Zheng, Wei
הוצא לאור ב Drug Discov Today (2018)

A High-throughput Screening Assay for Determining Cellular Levels of Total Tau Protein

מאת Dehdashti, Seameen J., Zheng, Wei, Gever, Joel R., Wilhelm, Robert, Nguyen, Dac-Trung, Sittampalam, Gurusingham, McKew, John C., Austin, Christopher P., Prusiner, Stanley B.
יצא לאור 2013

Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models

מאת Siramshetty, Vishal B., Shah, Pranav, Kerns, Edward, Nguyen, Kimloan, Yu, Kyeong Ri, Kabir, Md, Williams, Jordan, Neyra, Jorge, Southall, Noel, Nguyễn, Ðắc-Trung, Xu, Xin
הוצא לאור ב Sci Rep (2020)

How to Illuminate the Druggable Genome using Pharos

מאת Sheils, Timothy, Mathias, Stephen L., Siramshetty, Vishal B., Bocci, Giovanni, Bologa, Cristian G., Yang, Jeremy J., Waller, Anna, Southall, Noel, Nguyen, Dac-Trung, Oprea, Tudor I.
הוצא לאור ב Curr Protoc Bioinformatics (2020)

An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software

מאת Shah, Pranav, Kerns, Edward, Nguyen, Dac-Trung, Obach, R. Scott, Wang, Amy Q., Zakharov, Alexey, McKew, John, Simeonov, Anton, Hop, Cornelis E. C. A., Xu, Xin
הוצא לאור ב Drug Metab Dispos (2016)

The NCATS BioPlanet – An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics

מאת Huang, Ruili, Grishagin, Ivan, Wang, Yuhong, Zhao, Tongan, Greene, Jon, Obenauer, John C., Ngan, Deborah, Nguyen, Dac-Trung, Guha, Rajarshi, Jadhav, Ajit, Southall, Noel, Simeonov, Anton, Austin, Christopher P.
הוצא לאור ב Front Pharmacol (2019)

Global Substance Registration System: consistent scientific descriptions for substances related to health

מאת Peryea, Tyler, Southall, Noel, Miller, Mitch, Katzel, Daniel, Anderson, Niko, Neyra, Jorge, Stemann, Sarah, Nguyễn, Ðắc-Trung, Amugoda, Dammika, Newatia, Archana, Ghazzaoui, Ramez, Johanson, Elaine, Diederik, Herman, Callahan, Larry, Switzer, Frank
הוצא לאור ב Nucleic Acids Res (2020)

Examining the Chirality, Conformation and Selective Kinase Inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP...

מאת Jiang, Jian-kang, Ghoreschi, Kamran, Deflorian, Francesca, Chen, Zhi, Perreira, Melissa, Pesu, Marko, Smith, Jeremy, Nguyen, Dac-Trung, Liu, Eric H., Leister, William, Costanzi, Stefano, O’Shea, John J., Thomas, Craig J.
יצא לאור 2008