On the applicability of GPCR homology models to computer-aided drug discovery: a comparison between in silico and crystal structures of the β(2)-adrenergic receptor

le Costanzi, Stefano
Foilsithe 2008

Modeling G Protein-Coupled Receptors: a Concrete Possibility

le Costanzi, Stefano
Foilsithe 2010

Homology Modeling of Class A G Protein-Coupled Receptors

le Costanzi, Stefano
Foilsithe 2012

G protein-coupled receptors: computer-aided ligand discovery and computational structural analyses in the 2010s

le Costanzi, Stefano
Foilsithe in In Silico Pharmacol (2013)

In silico screening for agonists and blockers of the β(2) adrenergic receptor: implications of inactive and activated state structures

le Costanzi, Stefano, Vilar, Santiago
Foilsithe 2011

Predicting Biological Activities through QSAR Analysis and Docking-based Scoring

le Vilar, Santiago, Costanzi, Stefano
Foilsithe 2012

Unraveling the structure and function of G protein-coupled receptors through NMR spectroscopy

le Tikhonova, Irina G., Costanzi, Stefano
Foilsithe 2009

New Insights for Drug Design from the X-Ray Crystallographic Structures of G-Protein-Coupled Receptors

le Jacobson, Kenneth A., Costanzi, Stefano
Foilsithe 2012

Ligand and Structure-based Models for the Prediction of Ligand-Receptor Affinities and Virtual Screenings: Development and Application to the β(2)-Adrenergic Receptor

le Vilar, Santiago, Karpiak, Joel, Costanzi, Stefano
Foilsithe 2010

Prediction of passive blood-brain partitioning: straightforward and effective classification models based on in silico derived physicochemical descriptors

le Vilar, Santiago, Chakrabarti, Mayukh, Costanzi, Stefano
Foilsithe 2010

Seven Transmembrane-spanning Receptors for Free Fatty Acids as Therapeutic Targets for Diabetes Mellitus: Pharmacological, Phylogenetic, and Drug Discovery Aspects

le Costanzi, Stefano, Neumann, Susanne, Gershengorn, Marvin C.
Foilsithe 2008

Probing GPCR Structure: Adenosine and P2Y Nucleotide Receptors

le Jacobson, Kenneth A., Costanzi, Stefano, Deflorian, Francesca
Foilsithe 2013

Computational studies to predict or explain GPCR polypharmacology

le Jacobson, Kenneth A., Costanzi, Stefano, Paoletta, Silvia
Foilsithe in Trends Pharmacol Sci (2014)

Computing Highly Correlated Positions Using Mutual Information and Graph Theory for G Protein-Coupled Receptors

le Fatakia, Sarosh N., Costanzi, Stefano, Chow, Carson C.
Foilsithe 2009

In silico analysis of the binding of agonists and blockers to the β(2)-adrenergic receptor

le Vilar, Santiago, Karpiak, Joel, Berk, Barkin, Costanzi, Stefano
Foilsithe 2011

Molecular Evolution of the Transmembrane Domains of G Protein-Coupled Receptors

le Fatakia, Sarosh N., Costanzi, Stefano, Chow, Carson C.
Foilsithe 2011

Influence of the Structural Accuracy of Homology Models on Their Applicability to Docking-Based Virtual Screening: the β(2) Adrenergic Receptor as a Case Study

le Costanzi, Stefano, Cohen, Austin, Danfora, Abigail, Dolatmoradi, Marjan
Foilsithe in J Chem Inf Model (2019)

Development of Selective High Affinity Antagonists, Agonists, and Radioligands for the P2Y(1) Receptor

le Houston, Dayle, Costanzi, Stefano, Jacobson, Kenneth A., Harden, T. Kendall
Foilsithe 2008

Pharmacochemistry of the platelet purinergic receptors

le Jacobson, Kenneth A., Deflorian, Francesca, Mishra, Shilpi, Costanzi, Stefano
Foilsithe 2011

Molecular Structure of P2Y Receptors: Mutagenesis, Modeling, and Chemical Probes

le Jacobson, Kenneth A., Jayasekara, M.P. Suresh, Costanzi, Stefano
Foilsithe 2012