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In silico analysis of the binding of agonists and blockers to the β(2)-adrenergic receptor
Activation of G protein-coupled receptors (GPCRs) is a complex phenomenon. Here, we applied Induced Fit docking (IFD) in tandem with linear discriminant analysis (LDA) to generate hypotheses on the conformational changes induced to the β(2)-adrenergic receptor by agonist binding, preliminary to the...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2011
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119336/ https://ncbi.nlm.nih.gov/pubmed/21334234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2011.01.005 |
| Etiketak: |
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