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Docking-based virtual screening for ligands of G protein-coupled receptors: not only crystal structures but also in silico models
G protein-coupled receptors (GPCRs) regulate a wide range of physiological functions and hold great pharmaceutical interest. Using the β(2)-Adrenergic receptor as a case study, this article explores the applicability of docking-based virtual screening to the discovery of GPCR ligands and defines met...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035735/ https://ncbi.nlm.nih.gov/pubmed/21146435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2010.11.005 |
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