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G protein-coupled receptors: computer-aided ligand discovery and computational structural analyses in the 2010s

G protein-coupled receptors, or GPCRs, are a large superfamily of proteins found on the plasma membrane of cells. They are involved in most physiological and pathophysiological functions and constitute the target of the majority of marketed drugs. Although these receptors have been historically elus...

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Библиографические подробности
Опубликовано в: :In Silico Pharmacol
Главный автор: Costanzi, Stefano
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215811/
https://ncbi.nlm.nih.gov/pubmed/25505664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-9616-1-20
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