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Structural basis of G protein-coupled receptor/G protein interactions

The interaction of G protein-coupled receptors (GPCRs) with heterotrimeric G proteins represents one of the most fundamental biological processes. However, the molecular architecture of the GPCR/G protein complex remains poorly defined. In the present study, we applied a comprehensive GPCR/Gα chemic...

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Detalhes bibliográficos
Main Authors: Hu, Jianxin, Wang, Yan, Zhang, Xiaohong, Lloyd, John R., Li, Jianhua, Karpiak, Joel, Costanzi, Stefano, Wess, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104732/
https://ncbi.nlm.nih.gov/pubmed/20512139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.385
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