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Development of Selective High Affinity Antagonists, Agonists, and Radioligands for the P2Y(1) Receptor

The P2Y(1) receptor is a member of the P2Y family of nucleotide-activated G protein-coupled receptors, and it is an important therapeutic target based on its broad tissue distribution and essential role in platelet aggregation. We have designed a set of highly selective and diverse pharmacological t...

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Detalhes bibliográficos
Main Authors: Houston, Dayle, Costanzi, Stefano, Jacobson, Kenneth A., Harden, T. Kendall
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116925/
https://ncbi.nlm.nih.gov/pubmed/18673269
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