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[(32)P]2-iodo-N(6)-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate ([(32)P]MRS2500), a novel radioligand for quantification of native P2Y(1) receptors

1. Analysis of the P2Y family of nucleotide-activated G-protein-coupled receptors has been compromised by the lack of selective high-affinity, high-specific-radioactivity radioligands. We have pursued quantification of the P2Y(1) receptor through the development of a series of selective P2Y(1) recep...

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Detalhes bibliográficos
Main Authors: Houston, Dayle, Ohno, Michihiro, Nicholas, Robert A, Jacobson, Kenneth A, Harden, T Kendall
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1616982/
https://ncbi.nlm.nih.gov/pubmed/16299552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706453
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