تحميل...

MRS2500 [2-Iodo-N(6)-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate], a Potent, Selective, and Stable Antagonist of the Platelet P2Y(1) Receptor with Strong Antithrombotic Activity in Mice

The platelet P2Y(1) ADP receptor is an attractive target for new antiplatelet drugs. However, because of the lack of strong and stable antagonists, only a few studies have suggested that pharmacological inhibition of the P2Y(1) receptor could efficiently inhibit experimental thrombosis in vivo. Our...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hechler, Béatrice, Nonne, Christelle, Roh, Eun Joo, Cattaneo, Marco, Cazenave, Jean-Pierre, Lanza, François, Jacobson, Kenneth A., Gachet, Christian
التنسيق: Artigo
اللغة:Inglês
منشور في: 2005
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471153/
https://ncbi.nlm.nih.gov/pubmed/16236815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.105.094037
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