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Structurally related nucleotides as selective agonists and antagonists at P2Y(1) receptors
The P2Y(1) receptor responds to adenine nucleotides and is present in platelets, heart, smooth muscles prostate, ovary, and brain. A selective antagonist may be useful as an antithrombotic agent. We have analyzed the binding site of this G protein-coupled receptor using ligand design, site-directed...
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| Publicado no: | Farmaco |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313380/ https://ncbi.nlm.nih.gov/pubmed/11347970 |
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