And the winner is … RGS4!

Por Neubig, Richard R.
Publicado em 2008

Thinking Outside of the “RGS Box”: New Approaches to Therapeutic Targeting of Regulators of G Protein Signaling

Por Sjögren, Benita, Neubig, Richard R.
Publicado em 2010

FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex

Por Sjögren, Benita, Swaney, Steven, Neubig, Richard R.
Publicado no PLoS One (2015)

Polyplexed FCPIA (Flow Cytometry Protein Interaction Assay): A Novel High Throughput Screening Paradigm For RGS Protein Inhibitors

Por Roman, David L., Ota, Shodai, Neubig, Richard R.
Publicado em 2009

GNAI2 and Regulators of G protein Signaling as a potential Noonan Syndrome mechanism

Por Huang, Xinyan, Fu, Ying, Charbeneau, Raelene A., Neubig, Richard R.
Publicado em 2009

Novel form of crosstalk between G protein and tyrosine kinase pathways

Por Diversé-Pierluissi, María, Remmers, Ann E., Neubig, Richard R., Dunlap, Kathleen
Publicado em 1997

Conformational Dynamics of a Regulator of G-protein Signaling Protein Reveals a Mechanism of Allosteric Inhibition by a Small Molecule

Por Vashisth, Harish, Storaska, Andrew J., Neubig, Richard R., Brooks, Charles L.
Publicado em 2013

Cellular Mechanisms of Tissue Fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription

Por Tsou, Pei-Suen, Haak, Andrew J., Khanna, Dinesh, Neubig, Richard R.
Publicado em 2014

Use of Flow Cytometric Methods to Quantify Protein-Protein Interactions

Por Blazer, Levi L., Roman, David L., Muxlow, Molly R., Neubig, Richard R.
Publicado em 2010

Allosteric Inhibition of the Regulator of G Protein Signaling–Gα Protein–Protein Interaction by CCG-4986

Por Roman, David L., Blazer, Levi L., Monroy, C. Aaron, Neubig, Richard R.
Publicado em 2010

Small Molecule Inhibitors of Regulators of G Protein Signaling (RGS) Proteins

Por Turner, Emma M., Blazer, Levi L., Neubig, Richard R., Husbands, Stephen M.
Publicado em 2011

Digoxin-Mediated Upregulation of RGS2 Protein Protects against Cardiac Injury

Por Sjögren, Benita, Parra, Sergio, Atkins, Kevin B., Karaj, Behirda, Neubig, Richard R.
Publicado no J Pharmacol Exp Ther (2016)

Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics

Por Jovic, Andreja, Wade, Susan M., Neubig, Richard R., Linderman, Jennifer J., Takayama, Shuichi
Publicado em 2013

A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells

Por Aittaleb, Mohamed, Gao, Guang, Evelyn, Chris R., Neubig, Richard R., Tesmer, John J. G.
Publicado em 2009

A nanomolar potency small molecule inhibitor of Regulator of G protein Signaling (RGS) proteins

Por Blazer, Levi L, Zhang, Haoming, Casey, Emma M, Husbands, Stephen M, Neubig, Richard R
Publicado em 2011

Regulation of Protease-activated Receptor 1 Signaling by the Adaptor Protein Complex 2 and R4 Subfamily of Regulator of G Protein Signaling Proteins

Por Chen, Buxin, Siderovski, David P., Neubig, Richard R., Lawson, Mark A., Trejo, JoAnn
Publicado em 2014

Microfabricated Channel Array Electrophoresis for Rapid Characterization and Screening of Enzymes using RGS-G Protein Interactions as a Model System

Por Pei, Jian, Dishinger, John F., Roman, David L., Rungwanitcha, Chetwana, Neubig, Richard R., Kennedy, Robert T.
Publicado em 2008

Isoflurane-Induced Changes in Righting Response and Breathing are Modulated by RGS Proteins

Por Icaza, Eduardo E., Huang, Xinyan, Fu, Ying, Neubig, Richard R., Baghdoyan, Helen A., Lydic, Ralph
Publicado em 2009

Gα subunit coordinates with ephrin-B to balance self-renewal and differentiation in neural progenitor cells

Por Murai, Kiyohito, Qiu, Runxiang, Zhang, Heying, Wang, Jun, Wu, Chen, Neubig, Richard R., Lu, Qiang
Publicado em 2010

Hi-Fi transmission of periodic signals amid cell-to-cell variability

Por Jovic, Andreja, Wade, Susan M., Miyawaki, Atsushi, Neubig, Richard R., Linderman, Jennifer J., Takayama, Shuichi
Publicado no Mol Biosyst (2011)