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A nanomolar potency small molecule inhibitor of Regulator of G protein Signaling (RGS) proteins
Regulators of G-Protein signaling (RGS) proteins are potent negative modulators of signal transduction through G-Protein coupled receptors. They function by binding to activated (GTP-bound) Gα subunits and accelerating the rate of GTP hydrolysis. Modulation of RGS activity by small molecules is an a...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090679/ https://ncbi.nlm.nih.gov/pubmed/21329361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1019622 |
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