Oxygen Activation by Cytochrome P450 Monooxygenase

Por Hamdane, Djemel, Zhang, Haoming, Hollenberg, Paul
Publicado em 2008

Lead-acid Battery Intelligent Management System Based on TMS320F2812

Por Zhang Haoming, Peh Lian Soon, Wang Yinghai
Publicado em 2014-09-01

A Quantitative High-Throughput 96-well plate Fluorescence Assay for Mechanism-Based Inactivators of Cytochromes P450 Exemplified using CYP2B6

Por Kenaan, Cesar, Zhang, Haoming, Hollenberg, Paul F.
Publicado em 2010

Mechanism-Based Inactivation of Cytochrome P450 2B6 by Methadone through Destruction of Prosthetic Heme

Por Amunugama, Hemali T., Zhang, Haoming, Hollenberg, Paul F.
Publicado em 2012

Metabolic Activation of Mifepristone [RU486; 17β-Hydroxy-11β-(4-dimethylaminophenyl)-17α-(1-propynyl)-estra-4,9-dien-3-one] by Mammalian Cytochromes P450 and the Mechanism-Based...

Por Lin, Hsia-lien, Zhang, Haoming, Hollenberg, Paul F.
Publicado em 2009

Formation of the Thiol Conjugates and Active Metabolite of Clopidogrel by Human Liver Microsomes

Por Zhang, Haoming, Lau, Wei C., Hollenberg, Paul F.
Publicado em 2012

IMPROVED METHOD FOR ASSEMBLY OF HEMEPROTEIN NEURONAL NO-SYNTHASE HETERODIMERS

Por Morishima, Yoshihiro, Zhang, Haoming, Lau, Miranda, Osawa, Yoichi
Publicado no Anal Biochem (2016)

Formation of Both Heme and Apoprotein Adducts Contributes to the Mechanism-Based Inactivation of Human CYP2J2 by 17α-Ethynylestradiol

Por Lin, Hsia-lien, Zhang, Haoming, Hollenberg, Paul F.
Publicado no Drug Metab Dispos (2018)

Cryo-EM reveals the architecture of the dimeric cytochrome P450 CYP102A1 enzyme and conformational changes required for redox partner recognition

Por Su, Min, Chakraborty, Sumita, Osawa, Yoichi, Zhang, Haoming
Publicado no J Biol Chem (2020)

Kinetic Isotope Effects in Hydroxylation Reactions Effected by Cytochrome P450 Compounds I Implicate Multiple Electrophilic Oxidants for P450-Catalyzed Oxidations

Por Sheng, Xin, Zhang, Haoming, Hollenberg, Paul F., Newcomb, Martin
Publicado em 2009

Covalent Modification of Thr302 in Cytochrome P450 2B1 by the Mechanism-Based Inactivator 4-tert-Butylphenylacetylene

Por Lin, Hsia-lien, Zhang, Haoming, Jushchyshyn, Monica, Hollenberg, Paul F.
Publicado em 2010

Effects of a Commonly Occurring Genetic Polymorphism of Human CYP3A4 (I118V) on the Metabolism of Anandamide

Por Pratt-Hyatt, Matthew, Zhang, Haoming, Snider, Natasha T., Hollenberg, Paul F.
Publicado em 2010

Targeting of the highly conserved threonine 302 residue of cytochromes P450 2B family during mechanism-based inactivation by aryl acetylenes

Por Zhang, Haoming, Lin, Hsia-lien, Kenaan, Cesar, Hollenberg, Paul F.
Publicado em 2010

UNCOVERING THE ROLE OF HYDROPHOBIC RESIDUES IN CYTOCHROME P450-CYTOCHROME P450 REDUCTASE INTERACTIONS

Por Kenaan, Cesar, Zhang, Haoming, Shea, Erin V., Hollenberg, Paul F.
Publicado em 2011

Reaction of Human Cytochrome P450 3A4 with Peroxynitrite: Nitrotyrosine Formation on the Proximal Side Impairs its Interaction with NADPH-Cytochrome P450 Reductase

Por Lin, Hsia-lien, Kenaan, Cesar, Zhang, Haoming, Hollenberg, Paul F.
Publicado em 2012

Roles of Residues F206 and V367 in Human CYP2B6: Effects of Mutations on Androgen Hydroxylation, Mechanism-Based Inactivation, and Reversible Inhibition

Por Lin, Hsia-lien, Zhang, Haoming, Kenaan, Cesar, Hollenberg, Paul F.
Publicado no Drug Metab Dispos (2016)

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos

Por D’Agostino, Jaime, Zhang, Haoming, Kenaan, Cesar, Hollenberg, Paul F.
Publicado no Chem Res Toxicol (2015)

Mechanism-Based Inactivation of CYP2B1 and Its F-Helix Mutant by Two tert-Butyl Acetylenic Compounds: Covalent Modification of Prosthetic Heme Versus Apoprotein

Por Lin, Hsia-lien, Zhang, Haoming, Noon, Kathleen R., Hollenberg, Paul F.
Publicado em 2009

Defining the Structural Consequences of Mechanism-Based Inactivation of Mammalian Cytochrome P450 2B4 Using Resonance Raman Spectroscopy

Por Mak, Piotr J., Zhang, Haoming, Hollenberg, Paul F., Kincaid, James R.
Publicado em 2010

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Clopidogrel: Involvement of Both Covalent Modification of Cysteinyl Residue 475 and Loss of Heme

Por Zhang, Haoming, Amunugama, Hemali, Ney, Sarah, Cooper, Nyemade, Hollenberg, Paul F.
Publicado em 2011