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Thinking Outside of the “RGS Box”: New Approaches to Therapeutic Targeting of Regulators of G Protein Signaling
Regulators of G protein signaling (RGS) proteins are emerging as potentially important drug targets. The mammalian RGS protein family has more than 20 members and they share a common ∼120-residue RGS homology domain or “RGS box.” RGS proteins regulate signaling via G protein-coupled receptors by acc...
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Auteurs principaux: | , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981398/ https://ncbi.nlm.nih.gov/pubmed/20664002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.065219 |
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