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FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex

The ubiquitin-proteasome system for protein degradation plays a major role in regulating cell function and many signaling proteins are tightly controlled by this mechanism. Among these, Regulator of G Protein Signaling 2 (RGS2) is a target for rapid proteasomal degradation, however, the specific enz...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sjögren, Benita, Swaney, Steven, Neubig, Richard R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430315/
https://ncbi.nlm.nih.gov/pubmed/25970626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123581
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