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Digoxin-Mediated Upregulation of RGS2 Protein Protects against Cardiac Injury

Regulator of G protein signaling (RGS) proteins have emerged as novel drug targets since their discovery almost two decades ago. RGS2 has received particular interest in cardiovascular research due to its role in regulating G(q) signaling in the heart and vascular smooth muscle. RGS2(−/−) mice are h...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Sjögren, Benita, Parra, Sergio, Atkins, Kevin B., Karaj, Behirda, Neubig, Richard R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851323/
https://ncbi.nlm.nih.gov/pubmed/26941169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.231571
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